Brand & Generic Names
| Nemasol-Sodium |
|
| P.A.S. |
|
| Tubasal |
|
Basic Information
- Habit forming? No
- Prescription needed? Yes
- Available as generic? No
- Drug class: Antitubercular
Uses
Treatment for tuberculosis (TB).
Dosage & Usage Information
How to take:
Tablet--Swallow with liquid or food to lessen stomach
irritation.
Powder--Dissolve dose in water. Stir well and drink all
liquid.
When to take:
At the same times each day.
If you forget a dose:
Take as soon as you remember up to 2 hours
late. If more than 2 hours, wait for next scheduled dose (don't
double this dose).
What drug does:
Prevents growth of TB germs.
Makes TB germs more susceptible to other antituberculosis
drugs.
Time lapse before drug works:
6 months.
Don't take with:
Any other medicine without consulting your doctor or pharmacist
Overdose
SYMPTOMS:
Nausea, vomiting, diarrhea; rapid breathing;
convulsions.
WHAT TO DO:
- Dial 911 (emergency) or O (operator) for an ambulance or
medical help. Then give first aid immediately.
- See EMERGENCY Information.
Possible Adverse Reactions or Side Effects
Life-threatening:
In case of overdose, see Overdose section.
Common:
- Painful urination,
chills, low back pain,
nausea, vomiting.
- Diarrhea or
abdominal pain.
Infrequent:
- Confusion, blood
in urine.
- Headache; itchy,
dry, puffy skin; rash;
light sensitivity; sore
throat; fever; swelling
in front of neck;
decreased sex drive in
men; fatigue; weakness.
- Menstrual irregularities,
weight gain.
Rare:
Warnings & Precautions
Don't take if:
- You are allergic to aminosalicylate sodium, aspirin or other salicylates.
- Tablets have turned brownish or purplish.
Before you start, consult your doctor:
- If you have ulcers in stomach or duodenum.
- If you have liver or kidney disease.
- If you have epilepsy.
- If you have adrenal insufficiency.
- If you have heart disease or congestive heart failure.
- If you have cancer.
- If you have overactive thyroid.
Over age 60:
Adverse reactions and side effects may be more frequent and
severe than in younger persons.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Breast-feeding:
No proven problems. Consult doctor.
Infants & children:
Use only under medical supervision.
Prolonged use:
- Enlarged thyroid gland and decreased function.
- Talk to your doctor about the need for follow-up medical
examinations or laboratory studies to check liver function,
kidney function.
Skin & sunlight:
Increased sensitivity to light.
Driving, piloting or hazardous work:
No problems expected.
Discontinuing:
No problems expected.
Others:
- Treatment may need to continue for several years or
indefinitely.
- Periodic blood tests and liver and kidney function studies
recommended.
Possible Interaction with Other Drugs
| GENERIC NAME |
COMBINED EFFECT |
|
|
|
| ------------------------ |
----------------------- |
| Aminobenzoic acid |
Decreased effect of |
| (PABA) |
aminosalicylate sodium. |
| Anticoagulants, |
Increased anti- |
| oral* |
coagulant effect. |
| Anticonvulsants, |
Increased anti- |
| hydantoin* |
convulsant effect. |
| Aspirin |
Stomach irritation. |
| Barbiturates* |
Oversedation. |
| Folic acid |
Decreased effect of folic acid. |
| Probenecid |
Increased aminosalicylate sodium |
| |
effect. Possible toxicity. |
| Rifampin |
Decreased rifampin effect. |
| Sulfa drugs* |
Decreased effect of sulfa drugs. |
| Sulfinpyrazone |
Increased aminosalicylate sodium |
| |
effect. Possible toxicity. |
| Tetracyclines* |
Reduced absorption of |
| |
aminosalicylate sodium. Space |
| |
doses 3 hours apart. |
| Vitamin B-12 |
Decreased absorption of |
| |
vitamin B-12. |
Possible Interaction with Other Substances
| INTERACTS WITH |
COMBINED EFFECT |
| --------------- |
--------------- |
| Alcohol: |
Possible liver disease. |
|
|
|
| Beverages: |
None expected |
|
|
|
| Cocaine: |
None expected. |
|
|
|
| Foods: |
None expected. |
|
|
|
| Marijuana: |
None expected. |
|
|
|
| Tobacco: |
None expected, but tobacco smoking |
| |
may slow recovery. Avoid. |
