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ANTI-INFLAMMATORY ANALGESICS, NON-STEROIDAL (NSAIDS)
ANTI-INFLAMMATORY ANALGESICS, NON-STEROIDAL (NSAIDS)
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ANTI-INFLAMMATORY ANALGESICS, NON-STEROIDAL (NSAIDS)
BRAND & GENERIC NAMES
Advil MEFENAMIC ACID
Amersol Midol 200
Anaprox Motrin
Apo-Ibuprofen Nalfon
Apo-Naproxen Naprosyn
Apo-Piroxicam NAPROXEN
Apsifen Naxen
Apsifen-F Neuvil
ASPIRIN, BUFFERED Novopirocam
Brufen Novoprofen
CHOLINE SALICYLATE Nuprin
CHOLINE & MAGNESIUM Pamprin IB
SALICYLATES PHENYLBUTAZONE
Clinoril PIROXICAM
DIFLUNISAL Ponstan
Dolobid Ponstel
Feldene Progesic
FENOPROFEN Rufen
Fenopron SALICYLAMIDE
Haltran SALSALATE
IBUPROFEN SODIUM SALICYLATE
Ifen SULINDAC
INDOMETHACIN Synflex
KETOPROFEN Tolectin
MAGNESIUM SALICYLATE Tolectin DS
MECLOFENAMATE TOLMETIN
Meclomen Trendar
Medipren
BASIC INFORMATION
Habit forming? No
Prescription needed? No
Available as generic? Yes
Drug class: Anti-inflammatory (non-steroidal)
USES
Treatment for joint pain, stiffness, inflammation and swelling
of arthritis and gout.
Pain reliever.
Treatment for dysmenorrhea (painful or difficult menstruation).
Treats juvenile rheumatoid arthritis.
DOSAGE & USAGE INFORMATION
How to take:
Tablet or capsule -- Swallow with liquid or food to lessen stomach
irritation. If you can't swallow whole, crumble tablet and take
with liquid or food.
When to take:
At the same times each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Reduces tissue concentration of prostaglandins (hormones which
produce inflammation and pain).
Time lapse before drug works:
Begins in 4 to 24 hours. May require 3 weeks regular use for
maximum benefit.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Confusion, agitation, incoherence, convulsions, possible
hemorrhage from stomach or intestine, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS
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WHAT TO DO
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| Life-threatening:
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Hives, rash, intense itching, faintness soon after a dose (anaphylaxis in aspirin-
sensitive persons).
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Seek emergency treatment immediately.
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Common:
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Dizziness, nausea, pain.
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Continue. Call doctor when convenient.
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Headache.
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Continue. Tell doctor at next visit.
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Infrequent:
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Depression; drowsiness; ringing in ears; swollen feet, legs; constipation or
diarrhea; vomiting.
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Continue. Call doctor when convenient.
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Rare:
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Convulsions; confusion; rash, hives or itch; blurred vision; black, bloody, tarry stool; difficult
breathing; tightness in chest; rapid heartbeat; unusual bleeding or bruising; blood in urine;
jaundice; psychosis; frequent, painful urination; severe abdominal pain.
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Discontinue. Call doctor right away.
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Frequent, painful, or difficult urination; fatigue; weakness; menstrual irregularities; swollen
breasts in males; impotence.
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Continue. Call doctor when convenient.
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WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to aspirin or any non-steroid, anti-
inflammatory drug.
You have gastritis, peptic ulcer, enteritis, ileitis,
ulcerative colitis, asthma, heart failure, high blood pressure
or bleeding problems.
Patient is younger than 15.
Before you start, consult your doctor:
If you have epilepsy.
If you have Parkinson's disease.
If you have been mentally ill.
If you have had kidney disease or impaired kidney function.
Pregnancy:
Studies inconclusive on harm to unborn child. Decide with your
doctor whether drug benefits justify risk to unborn child.
Infants & children:
Not recommended for anyone younger than 15. Use only under
medical supervision.
Prolonged use:
Eye damage.
Reduced hearing.
Sore throat, fever.
Weight gain.
Skin & sunlight:
Possible increased sensitivity to sunlight.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you
drink alcohol or take medicine affecting alertness and reflexes,
such as antihistamines, tranquilizers, sedatives, pain medicine,
narcotics and mind-altering drugs.
Discontinuing:
Don't discontinue without consulting doctor. Dose may require
gradual reduction if you have taken drug for a long time. Doses
of other drugs may also require adjustment.
Others:
No age-related problems expected.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| ACE inhibitors: |
May decrease ACE |
| captopril, enalapril, |
inhibitor effect. |
| lisinopril (see Drugs |
| Glossary) |
| Anticoagulants (oral, |
Increased risk of |
| see Drugs Glossary) |
bleeding. |
| Aspirin |
Increased risk of stomach ulcer. |
| Beta-adrenergic |
Decreased antihypertensive |
| blockers (see |
effect. |
| Drugs Glossary) |
| Cortisone drugs |
Increased risk of stomach ulcer. |
| Diuretics |
May decrease diuretic |
| (see Drugs Glossary) |
effect. |
| Lithium |
Possible increase in effect and |
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toxicity. |
| Methotrexate |
May increase toxicity. |
| Minoxidil |
Decreased minoxidil effect. |
| Oxyphenbutazone |
Possible stomach ulcer. |
| Phenylbutazone |
Possible stomach ulcer. |
| Probenecid |
Increased NSAID effect. |
| Thyroid hormones |
Rapid heartbeat, blood-pressure |
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rise. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
Increased pain relief from NSAIDs. |
| Tobacco: |
None expected. |
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From Complete Guide to Pediatric Symptoms, Illness & Medications by H. Winter Griffith, M.D. Copyright by Putnam Publishing
Group. Electronic rights by Medical Data Exchange.
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