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APPENDIX 1:
BLOOD IMMUNOGLOBULIN LEVELS IN VARIOUS DISORDERS
DISEASES IgG IgA IgM
IMMUNOGLOBULIN
DISORDERS
Agammaglobulinemia Decreased Decreased Decreased
Ataxia-telangiectasia Normal Decreased Normal
IgA globulinemia Normal Decreased Normal
Lymphoid aplasia
Type-I dysgammaglobulinemia (selective IgG and IgAor
deficiency)
Decreased Decreased Normal
Increased Type-II
dysgammaglobulinemia
(absent IgA and IgM)
Normal Decreased Decreased

MULTIPLE MYELOMA, MACROGLOBULINEMIA, LYMPHOMAS

Acute lymphocytic leukemia Normal Decreased Normal
Chronic myelocytic leukemia Decreased Decreased Decreased
Heavy-chain disease
(Franklin's disease) Decreased Decreased Decreased
Hodgkin's disease Normal Normal Normal
IgA myeloma Decreased Increased Decreased
IgG myeloma Increased Decreased Decreased
Macroglobulinemia Decreased Decreased Increased
-----------------
HEPATIC DISORDERS
Biliary cirrhosis Normal Normal Increased
Hepatitis Increased Increased Increased
Hepatoma Normal Normal Decreased
Laennec's cirrhosis Increased Increased Normal
---------------
OTHER DISORDERS

Nephrotic syndrome Decreased Decreased Normal
Pulmonary tuberculosis Increased Normal Normal
Rheumatoid arthritis Increased Increased Increased
Systemic lupus Increased Increased Increased
erythematosus
Trypanosomiasis Normal Normal Increased

 
From Complete Guide to Medical Tests by H. Winter Griffith, M.D. Copyright by Fisher Books. Electronic rights by Medical Data Exchange.

 

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