| TYPE OF CRYOGLOBULIN |
ABNORMAL AMOUNTS IN BLOOD |
WHAT "ABNORMAL" MAY INDICATE |
TYPE I
Monoclonal
cryoglobulin |
Greater than 5mg/ml |
- Chronic lymphocytic leukemia.
- Myeloma.
- Waldenstrom's macroglobulinemia.
|
TYPE II
Mixed
cryoglobulin |
Greater than 1mg/ml |
- Mixed essential globulinemia.
- Rheumatoid arthritis.
- Sjogren's syndrome.
|
TYPE III
Mixed poly-
clonal
cryoglobulin |
Less than 1mg/ml |
- Acute viral hepatitis (50% below 80 mcg/ml)
- Chronic, active hepatitis.
- Cytomegalovirus infections.
- Infectious mononucleosis.
- Infective endocarditis.
- Kala-azar.
- Leprosy.
- Post-streptoccocal glomerulonephritis.
- Primary biliary cirrhosis.
- Rheumatoid arthritis.
- Systemic lupus erythematosus.
- Tropical splenomegaly syndrome.
|
